Zhixin Tian

KEYNOTE INVITED SPEAKERS

Zhixin Tian

Tongji University, Shanghai, China

Dr. Tian obtained his PhD degree from Institute of Chemistry, Chinese Academy of Sciences under the supervision of Prof. Qi-he Zhu and Zi-chao Tang in 2003. From 2004-2011, Dr. Tian did his postdoctoral research in University of Minnesota with Prof. Steven Kass and Pacific Northwest National Laboratory with Prof. Richard Smith and Ljiljana Paša-Tolić. In September of 2011,Dr. Tian started his independent research at Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Since 2013, Dr. Tian has been a full professor at Tongji University with research interest in MS-based Proteomics. Prof. Tian’s group has invented the “isotopic mass-to-charge ratio and envelope, iMEF” search algorithm of biological mass spectra to accommodate their new feature of often missing mono-isotopic peaks. With this new and accurate search algorithm, intact protein DB search engine ProteinGoggle, phosphosite localization tool P-bracket, N-glycan DB search engine GlySeeker and intact N-glycopeptide DB search engine GPSeeker have been developed and successfully applied to both qualitative and quantitative PTMomics. The most recent focus is quantitative site- and structure-specific N-glycoproteomics and its application in biomarker discovery of cancers as well as cancer stem cells.