Mathias Uhlen research is focused on protein science, antibody engineering and precision medicine and ranges from basic research in human and microbial biology to more applied research, including clinical applications in cancer, infectious diseases, cardiovascular diseases, autoimmune diseases and neurobiology. His research has resulted in more than 600 publications and he is co-founder of 12 biotech companies. Since 2003, he has led an international effort to systematically map the human proteome and transcriptome to create a Human Protein Atlas using antibodies and various omics technologies. This effort has so far resulted the Tissue Atlas (2015) showing the distribution of proteins across human tissues and organs, the Cell Atlas (2016) showing the subcellular location of human proteins in single cells and the Pathology Atlas (2017) showing how cancer patient survival is tied to RNA and protein levels. He is member of the National Academy of Engineering (NAE) in USA, the Royal Swedish Academy of Science (KVA), the Swedish Academy of Engineering Science (IVA) and the European Molecular Biology Organization (EMBO). He is the President of the European Federation of Biotechnology and is chairing the International Working Group for Antibody Validation (IWGAV). From 2010-2015, he was the founding Director of the Science for Life Laboratory (SciLifeLab) which is a Swedish national center for molecular bioscience.
Mathias Uhlen has been selected for the MCP Lectureship Award. Molecular & Cellular Proteomics, an official publication of the American Society for Biochemistry and Molecular Biology, introduced its sponsored lectureship series as part of its 10th anniversary celebration in 2011. Each lecturer is a leader in the field of proteomics who presents his or her particular research and interests, with the intent to expand on proteomics’ potential to ask (and answer) increasingly complex questions associated with health, energy, food supply and the environment. The lectureships are given at germane meetings and symposia throughout the year, and the lecturers are chosen by the organizers of those meetings. Each lecturer is presented with a crystal plaque to commemorate the occasion.