HIPP Program

HIPP Program

Abstract submission closes Thursday 1 August 2019.  

Registration: Early bird (expires 1 August 2019) - Regular $150 - Student $120
After early bird the following registration rates will apply - Regular $250 - Student $170

On behalf of the organising committee, we are delighted to welcome you to the Human Proteome Organisation satellite meeting focussed on the Human Immunopeptidome (HUPO-HIPP). The meeting will be held as a one-day workshop on Saturday 14th September at the Adelaide Convention Centre and will bring together leading scientists from academia and industry to showcase their latest findings in the field of immunopeptidomics across three major themes:

  • New methods and applications in immunopeptidomics
  • Immunopeptidomics in health and disease
  • Round table discussion on global standardisation of workflows as part of the establishment of a Precision Immunology Consortium

We are proud to announce that we have three excellent international keynote speakers confirmed:

Albert Heck | Utrecht University, Netherlands
Etienne Caron | University of Montréal, Canada
Nicola Ternette | University of Oxford, UK

In addition, a number of submitted abstracts will be awarded oral presentations.

The meeting will conclude with a networking and poster session over drinks, followed by a conference dinner (location to be announced).

This is the third meeting of the HUPO-HIPP initiative after it was founded in 2015. The initiative strives to enable (i) method and technology development, (ii) standardisation, (iii) effective data sharing, and (iv) education, as defined by Caron et al. Immunity, 2017.

We look forward to welcoming you in Adelaide and hope to see you stay on for the HUPO 18th Annual Congress 

Organising committee
Prof. Anthony Purcell (Chair)
Dr. Nathan Croft
Dr. Pouya Faridi
Dr. Patricia Illing
Dr. Sri Ramarathinam

HIPP 2019

Venue : Riverbank 5 – Adelaide Convention Center, North Terrace

8:30-9:00     Registration

9:00-9:50     Welcome and Plenary Session

Chair: Tony Purcell (Monash University, Australia))

Plenary: Albert Heck (Utrecht University, Netherlands)

How well do we know the HLA ligandome?

9:50-10:10   Jennie Lill (Genentech, USA)

Characterizing Oncogenic MHC Ligandomes for Novel Therapeutic Targets

10:10-10:30 Patricia Illing (Monash University, Australia)

Utilising LC-MS/MS to identify novel targets in influenza infection

10:30-11:00 Morning Tea

11:00-13:00 New Methods and applications in immunopeptidomics

Chairs: Pouya Faridi, Monash University & Nicola Ternette, Oxford University

11:00-11:30 Keynote: Etienne Caron (Université de Montréal, Canada)

The Human Immuno-Peptidome Project: a roadmap to predict and treat immune diseases

11:30-11:45 Christopher Rose (Genetech, USA)

Translational immunopeptidomics supporting individualized neoantigen specific treatments and the characterization of therapeutic immunogenicity

11:45-12:00 Emma Jappe (Evaxion, Denmark)

High-throughput mass-spectrometry-based analysis of endogenous peptide-HLA I thermal stability improves the prediction of T cell epitopes

12:00-12:15 Mogjib Salek (German Cancer Research Center (DKFZ))

Detection of Ultra-low abundant epitopes by targeted mass spectrometry

12:15-12:30 James Waddington (University of Liverpool, UK)

β-lactam protein binding leads to the presentation of novel MHC peptides, generating a potential immunogen for drug-hypersensitive reactions

12:30-12:45 Kate Scull (Monash University, Australia)

Unconventional epitope discovery: a novel bioinformatics workflow for immunopeptidogenomics

12:45-13:00 Yuriko Minegishi (Japanese Foundation for Cancer Research)

Simple and efficient HLAp-ligandomics using high-field asymmetric waveform ion mobility spectrometry (FAIMS)

13:00-14:00 Lunch | Poster Session and Trade Display

14:00-16:15 Immunopeptidomics in Health and Disease

Chairs: Etienne Caron and Patricia Illing

14:00-14:30 Keynote: Nicola Ternette (Oxford University, UK)

Value and limitations of LC-MS HLA-ligandome data for antigen discovery and vaccine development

14:30-14:45 Kirti Pandey (Monash University, Australia)

Identification of heteroclitic neoantigens in pontine gliomas for immunotherapy

14:45-15:00 Takeshi Kawamura (University of Tokyo, Japan)

Proteogenomics-based identifying neoantigens in refractory cancers using xenograft mice

15:00-15:15 Sonali Mohan (QIMR Berghofer Medical Research Institute, Australia)

MHC peptidome analysis to identify and characterize cancer neo-antigens

15:15-15:30 Wei Wu (Utrecht University, Netherlands)

Single cell clonal diversity in HLA class I peptide presentation: case-study from a single CRC patient

15:30-15:45 Chen Li (ETH Zürich, Switzerland)

Computational identification of mutated p-HLAs in the melanoma immunopeptidome by cross-referencing cancer specific proteome database

15:45-16:00 Manuel Fuentes (University of Salamanca, Spain)

Deciphering tumoral biology by immunoproteogenomics approaches: Novel therapeutic targets and neoantigens in chronic lymphocytic leukemia & leptomeningeal diseases

16:00-16:15 Sri Ramarathinam (Monash University)

Immunopeptidomics of tumour biopsies – how low can you go?

16:15-16:45 Coffee Break

16:45-17:45 Roundtable Discussion

Chair: Andreas Huhmer with a panel of distinguished guests and speakers

  • Towards standardisation of workflows
  • Challenges in bioinformatics for immunopeptidomics
  • Establishment of a precision immunology consortium

17:45-19:30 Drinks with Canapés | Poster session and trade display

19:30-22:30 Dinner (Included) – Gilbert Suite

Please join us as our guests for a special dinner to commemorate this day and enjoy a taste of South Australia in the Gilbert Suite – a short walk from the conference room this is Adelaide Convention Centres’ Premium Venue. Continue networking in a relaxed setting overlooking the stunning River Torrens and surrounds with premium South Australian Wines and produce.

Invited Speaker

Etienne Caron

Nicola Maria Nathalie Ternette

Albert Heck

Principal Partners

Executive Sponsors